Northwestern University scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic lateral sclerosis), a swift and fatal neurodegenerative disease that paralyzes its victims.
University of Houston biomedical researcher Sheeren Majd is reporting the development and testing of a new nano-carrier as a potential treatment to deliver highly toxic medicine to glioblastomas, the most common and aggressive form of primary brain tumors.
Credit: Mount Sinai Health System
Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. This process, called cognitive control, is frequently dysregulated in a wide range of psychiatric disorders. The team s research, published February 19 in
Neuron, also suggests that neurostimulation of this brain pathway could provide an important mechanism for attention adjustments following behavioral errors.
When errors are committed, such as missing a stop sign or running a red light while driving, it s important for our survival to immediately adapt behavior by paying more attention to prevent further errors. This ability to adapt behavior after erroneous actions is one of the key components of human cognitive control.
Building upon previous work studying the brain and politics, Ingrid Haas, associate professor of political science affiliated with Nebraska s Center for Brain, Biology and Behavior, examined the insula and anterior cingular cortex in 58 individuals using functional Magnetic Resonance Imaging and learned that the human brain processes politically incongruent statements differently.
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Study Shows Voluntary Running Reduces Neuromuscular Decline In Aging Mice
Their study, published online in Neurobiology of Aging,investigated aging rodents that underwent voluntary running exercise between the ages of 22 and 27 months, which represents roughly 55 to 80 years of age in humans.
“These experiments showed that running significantly improved the neuromuscular decline in mice that underwent running compared to sedentary mice. Our findings support the mantra of ‘use it or lose it’ in regards to the connection between the nervous system and muscles, namely the neuromuscular junction,” said senior author Dr. W. David Arnold, neuromuscular specialist and associate professor at Ohio State Wexner Medical Center.